The study included 621 cases of prostate and 1205 of breast cancer with 872 male and 1321 female population controls. Participants were interviewed on timing of meals and sleep, and they completed a Food Frequency Questionnaire.
Compared with individuals sleeping immediately after supper, those sleeping 2 or more hours after supper had a 20% reduction in cancer risk for breast and prostate cancer combined and in each cancer individually. A similar protection was observed in individuals having supper before 9pm compared with supper after 10pm.
The findings stress the importance of evaluating the body’s internal clock—or circadian rhythms—in studies on diet and cancer, and the need to develop dietary recommendations for cancer prevention that focus not only on type and quantity of food intake.
“If the findings are confirmed, they will have implications for cancer prevention recommendations that currently do not take meal timing into account” said lead author Dr. Manolis Kogevinas, of ISGlobal, in Barcelona. “The impact could be especially important in cultures such as those of southern Europe where people tend to have supper late.”
Full bibliographic information
“Effect of mistimed eating patterns on breast and prostate cancer risk (MCC-Spain Study).”
International Journal of Cancer; Published Online: July 17, 2018. (DOI: 10.1002/ijc.31649).