This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
Recurrent miscarriage: diabetes drug could ... An existing drug can be used to improve the womb for pregnancy, ... (08 Jan 2020)
Nerve Stimulation May Benefit Women with ... A treatment involving electrical nerve stimulation helped women ... (08 Jan 2020)
Cancer drugs could potentially treat COPD, ... New research from the University of Sheffield shows a certain ... (08 Jan 2020)
Tea drinkers live longer Drinking tea at least three times a week is linked with a longer ... (08 Jan 2020)

Low Scores on Memory and Thinking Tests May Signal Alzheimer’s Earlier than Thought

alzheimers2A new study by researchers from Rush University Medical Center suggests that errors on memory and thinking tests may signal Alzheimer’s up to 18 years before the disease can be diagnosed.
“The changes in thinking and memory that precede obvious symptoms of Alzheimer’s disease begin decades before,” said study author Kumar B. Rajan. “While we cannot currently detect such changes in individuals at risk, we were able to observe them among a group of individuals who eventually developed dementia due to Alzheimer’s.”
For the study, 2,125 European-American and African-American people from Chicago with an average age of 73 without Alzheimer’s disease were given tests of memory and thinking skills every three years for 18 years.
Twenty-three percent of African-Americans and 17 percent of European-Americans developed Alzheimer’s disease during the study. Those who scored lower overall on the memory and thinking tests had an increased risk of developing the disease. During the first year of the study, people with lower test scores were about 10 times more likely to be diagnosed with Alzheimer’s disease than people with higher scores, with the odds increasing by 10 for every standard deviation that the score was lower than the average.
Based on tests completed 13 to 18 years before the final assessments took place, one unit lower in performance of the standardized cognitive test score was associated with an 85 percent greater risk (relative risk of 1.85) of future dementia. “While that risk is lower than the same one unit lower performance when measured in the year before dementia assessment, the observation that lower test scores 13 to 18 years later indicates how subtle declines in cognitive function affect future risk,” said Rajan.
“A general current concept is that in development of Alzheimer’s disease, certain physical and biologic changes precede memory and thinking impairment. If this is so, then these underlying processes may have a very long duration. Efforts to successfully prevent the disease may well require a better understanding of these processes near middle age,” said Rajan.


Source Newsroom: Rush University Medical Center
Citations
Neurology

Highlights

  • Nescafé 3 in1 LifeCycle HEROES return from South Asia

    Donations for Nescafé 3in1 LifeCycle Challenge 2019 can be sent via sms: 5061 7370 = €2.33; 5061 8920 = €6.99; 5061 9229 = €11.65; or via a call to 5160 2020 = €10, 5170 2005 = €15; and 5180 2006 = €25. Bank details are Swift code VALLMTMT, IBAN number MT 18 VALL 22013000000014814521017, Bank name Bank of Valletta, Account number 14814521017.

    Read more...
  • Give a Gift this Christmas which gives back

    The story of medicine is the story of civilization, from an ancient craft of primitive magic and religion to the sophisticated field of science and technology of today.

    Read more...

Join

Connect with other Medical Professionals on fb in a closed facebook group

Login

Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…