This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
Recurrent miscarriage: diabetes drug could ... An existing drug can be used to improve the womb for pregnancy, ... (08 Jan 2020)
Nerve Stimulation May Benefit Women with ... A treatment involving electrical nerve stimulation helped women ... (08 Jan 2020)
Cancer drugs could potentially treat COPD, ... New research from the University of Sheffield shows a certain ... (08 Jan 2020)
Tea drinkers live longer Drinking tea at least three times a week is linked with a longer ... (08 Jan 2020)

Oral contraceptives have prevented about 200000 cases of endometrial cancer in the last decade

thepill1aUse of oral contraceptives (usually referred to as “the pill”), even for just a few years, gives substantial long-term protection against endometrial cancer, and the longer the pill is used the greater the reduction in risk, according to a detailed re-analysis of all the available evidence, published in The Lancet Oncology journal.
Researchers from the Collaborative Group on Epidemiological Studies on Endometrial Cancer estimate that in the past 50 years (1965-2014) about 400000 cases of endometrial cancer have been prevented by oral contraceptive use in high-income countries, including about 200000 in the last decade (2005-2014).
“The strong protective effect of oral contraceptives against endometrial cancer – which persists for decades after stopping the pill – means that women who use it when they are in their 20s or even younger continue to benefit into their 50s and older, when cancer becomes more common,”* explains study author Professor Valerie Beral, from the University of Oxford in the UK.
She added “Previous research has shown that the pill also protects against ovarian cancer. People used to worry that the pill might cause cancer, but in the long term the pill reduces the risk of getting cancer.”
The researchers pooled data on 27276 women with endometrial cancer in 36 studies from North America, Europe, Asia, Australia, and South Africa—virtually all the epidemiological evidence ever collected on the effect of oral contraceptives.
The findings reveal that every 5 years of oral contraceptive use reduces the risk of endometrial cancer by about a quarter (figure 1). In high-income countries, 10 years of oral contraceptive use reduces the risk of developing endometrial cancer before age 75 from 2.3 to 1.3 cases per 100 users (figure 4).
Although oestrogen doses in oral contraceptives have decreased appreciably over the years, with pills in the 1960s typically containing more than double the oestrogen dose of pills in the 1980s, the reduction in endometrial cancer risk was at least as great for women who used the pill during the 1980s as for those who used it in earlier decades. These results suggest that the amount of hormones in the lower-dose pills is still sufficient to reduce the incidence of endometrial cancer, say the authors.
The proportional risk reduction did not vary substantially by women’s reproductive history, adiposity (amount of body fat), alcohol use, tobacco use, or ethnicity.
According to study author Dr Naomi Allen, also from the University of Oxford, UK, “The existing evidence suggests that medium-to-long-term use of oral contraceptives (ie, for 5 years or longer) results in substantially reduced risk of endometrial cancer. Over the past 50 years (1965-2014), we estimate that about 400000 endometrial cancers have been prevented in women before the age of 75 years in high-income countries through the use of oral contraceptives, with about 200,000 prevented during the last decade (2005-14).”



Source: The Lancet Oncology

Highlights

  • Nescafé 3 in1 LifeCycle HEROES return from South Asia

    Donations for Nescafé 3in1 LifeCycle Challenge 2019 can be sent via sms: 5061 7370 = €2.33; 5061 8920 = €6.99; 5061 9229 = €11.65; or via a call to 5160 2020 = €10, 5170 2005 = €15; and 5180 2006 = €25. Bank details are Swift code VALLMTMT, IBAN number MT 18 VALL 22013000000014814521017, Bank name Bank of Valletta, Account number 14814521017.

    Read more...
  • Give a Gift this Christmas which gives back

    The story of medicine is the story of civilization, from an ancient craft of primitive magic and religion to the sophisticated field of science and technology of today.

    Read more...

Join

Connect with other Medical Professionals on fb in a closed facebook group

Login

Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…