In the 528-patient study, median time to recovery was 14 days for patients who underwent observation and 12 days for those who received antibiotics. No significant differences between the observation and antibiotic treatment groups were found concerning rates of complicated diverticulitis, ongoing diverticulitis, recurrent diverticulitis, surgery, hospital readmission, adverse events, and mortality. Hospital stay was significantly shorter in the observation group (2 versus 3 days).
The findings are published in the British Journal of Surgery.
Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis. British Journal of Surgery.